MZ2SU

Prompt

1.2.1.36

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. retinal dehydrogenase.

AI Generated Sequence

500 AAs

MAPTHRVKLNDGKNIPIWGFGTWASKPKPGEVYKSVKVAIDVGYRHFDCADVYKNEAEVGKAFQAKWKEGVAKREELFIVSKLWCTSHRKDLVRPTLEKTLNKLQLDYVDLYLIHFPFSFKAGEELYPVDENKTIPDSTFDYLATWEAMEECVDLGWVPNIGVSNFNHKQIARILNCGPTLKPVNTQVELHPYLLQNKLIEGFCQPKGVNIVTYGPLGSQRSPWAVHPDSKVLFDSTTVAAIAKKHKTAAQVLIRFQVQRGNLVIIVSKEPERIKENLQIFDFFLFGSGMMCIASLERNLHVEILDQFVEKHKYPFAEELFGDPFNPETKMGAHISKEHLKDLLSYIIDGKKEGAKLLCGGEAHEGNGYFIKPTVFADVTQDMKIAKETIFGPVVHILRFKTTEEAIAIANDTNYGLAAGVFTQDLKRAYLIAEELDRGRTVWINSYLVAPQRPFGGFKSGGIGRNLGKYGLDRYQPKTSVSIDMKLKSNWGEEPYKLPV

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.2
NLMSIM	70.0
AACOMP	93.4
Seqdif (SeqID)	46.3 (XP_039401538.1)
Structdif (F-Target)	4.7 (4wdw A)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.226
Aldehyde/histidinol dehydrogenase	0.089
Aldehyde reductase	0.085
Aldehyde dehydrogenase family protein	0.054
Aldehyde dehydrogenase family 1 member B1	0.030
Aldehyde oxidoreductase	0.028