MZ22Z

Prompt

5.4.99.21

Isomerases. Intramolecular transferases. Transferring other groups. 23S rRNA pseudouridine(2604) synthase.

AI Generated Sequence

242 AAs
MTDERLQKYLASAGHGSRREAERLIAEGRVTVNGKVVTELGDRVDPGTDRVEVDGRRVEAEEPRVYLAFNKPEGVLTTMRDPEGRPTVFDRLPRLRGERVFHVGRLDKNSEGLLLLTNDGELANRLMHPSYGVEKTYLVRVVGPVDRAMLERLAEGVELEDGPARFDDVRIVEGGGRNSVFEVTLHEGRNRQVRRMFEAVGHPVTRLVRVRYGPVTLGDLPRGSYRELTEAEVARLRELVGL

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT93.6
NLMSIM85.0
AACOMP85.5
Seqdif (SeqID)40.3 (ALU39832.1)
Structdif (F-Target)7.2 (3dh3 D)

ProtNLM

NameScore
5.4.99.-0.512
Pseudouridine synthase0.477
5.4.99.220.003
Ribosomal large subunit pseudouridine synthase B0.002
RRNA pseudouridine synthase0.001
RluA family pseudouridine synthase0.001
Designed by MP, using an AMD MI250 GPU