MZ1X2

Prompt

7.1.1.1

Translocases. Catalysing the translocation of hydrons. Hydron translocation or charge separation linked to oxidoreductase reactions. proton-translocating NAD(P)(+) transhydrogenase.

AI Generated Sequence

500 AAs

MKIGIPKETLAGETRVAATPKTVEQLLKLGFDVAVESGAGALASFDDAAYEAAGATIVGAAEVWASDIILKVNAPTDDEIALLREGATLVSFIWPAQNPELMEKLAARKITVMAMDAVPRISRAQSMDALSSMANIAGYRAVIEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAAGSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFNKRAMELFAAQAKEVDIIITTALIPGKPAPKLITREMVASMKAGSVIVDLAAQNGGNCEYTVADKVFTTDNGVKVIGYTDLVGRLPTQSSQLYGTNLVNLVKLLCPEKDGNIVVDFDDVVVRGVTVIRDGEITWPAPPIQVSAQPQAAKAAPKEVKPEEKPMSPTRKYALMALGIALFGWLANVAPAEFLGHFTVFALACVVGYYVIWNVSHALHTPLMSVTNAISGIIVVGALLQIGHGGWVVTFLAFIAVLIASINIFGGFTVT

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.5
NLMSIM	70.0
AACOMP	91.5
Seqdif (SeqID)	13.2 (WP_044176822.1)
Structdif (F-Target)	2.0 (1x15 A)

ProtNLM

Name	Score
NAD(P) transhydrogenase subunit alpha	0.538
7.1.1.1	0.444
Nicotinamide nucleotide transhydrogenase subunit alpha	0.007
Proton-translocating NAD(P)(+) transhydrogenase	0.002
1.6.1.2	0.002
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha	0.001