MYWCM

Prompt

1.14.13.33

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. 4-hydroxybenzoate 3-monooxygenase [NAD(P)H].

AI Generated Sequence

295 AAs
MRTQVAIIGAGPSGLLLGQLLHKAGIDNIILERKSGDYVLGRIRAGVLEQGTVDLLREAGVSERMHAEGLPHDGFELAFDGKRHRIDLKGLTGGKHVMVYGQTEVTRDLMDARDAAGGLTIYEAENVQPHDFKSDSPYVTYKKDGETHRLDCDYIAGCDGFHGVSRQSIPKESIKEYEKVYPFGWLGILSDTPPVSHELIYANHERGFALCSMRSPTRSRYYVQCSLPDKVEDWSDERIWNELKARLPDEVAERLVTGPSIEKSIAPLRSFVVEPMRYGRLFLAGDAAHIVPPMG

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT93.1
NLMSIM95.0
AACOMP94.0
Seqdif (SeqID)17.6 (WP_305794813.1)
Structdif (F-Target)2.1 (1bf3 2)

ProtNLM

NameScore
4-hydroxybenzoate 3-monooxygenase0.493
1.14.13.20.426
4-hydroxybenzoate hydroxylase0.031
P-hydroxybenzoate hydroxylase0.029
P-hydroxybenzoate 3-monooxygenase0.003
4-hydroxybenzoate hydroxylase protein0.001
Designed by MP, using an AMD MI250 GPU