MYLO5

Prompt

6.3.5.2

Ligases. Forming carbon-nitrogen bonds. Carbon--nitrogen ligases.with glutamine as amido-N-donor. GMP synthase (glutamine-hydrolyzing).

AI Generated Sequence

285 AAs

MEKIVVLDFGSQYTQLIARRVRELGVYCEIVPYNKIEEIKELNPLGIILSGSPSSVYDENAPKIDLSIFELKIPLLGVCYGAQYLAHTLGGKVERSDTREYGRANLIKIDKNDELFKGVKENSQVWMSHGDTISKLPENFEIIASTESVKVAAMKNEEKKIYGVQFHPEVTHTVDGKKILENFLVDICKAKQDWTPESFVEETVAELKEKVGDEKVLLGLSGGVDSTVAAVLLHKAIGKNLTCIFVDNGLLRKDEFENVLDSYEGMHLNVIGVDASKRFYDALAG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	91.3
NLMSIM	95.0
AACOMP	91.4
Seqdif (SeqID)	31.2 (WP_103790239.1)
Structdif (F-Target)	7.0 (1wl8 A)

ProtNLM

Name	Score
GMP synthase (Glutamine-hydrolyzing)	0.370
Glutamine-hydrolyzing GMP synthase	0.254
6.3.5.2	0.247
GMP synthase (Glutamine-hydrolyzing), N-terminal domain protein	0.024
GMP synthase [glutamine-hydrolyzing]	0.017
GMP synthase [glutamine-hydrolyzing], amidotransferase subunit / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit	0.014