MYIIE

Prompt

1.13.11.53

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. acireductone dioxygenase (Ni(2+)-requiring).

AI Generated Sequence

234 AAs

MSSIRWFDGNELDENPEVKSDLEEGIILDEKIGVRFERWPDAESLPDDEKEEEILAYFDAEIDRLVAEGGYKTRDVISISPDNPKLPEMRAKFLEVHTHSDDEVRFFVSGSGLFLHIHKDEVFRYLCEEGDFISVPANTLHWFDMGPDPWVTALRFFTDPEGWVGHFYTETADKQFPRFEEDDEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	74.6
NLMSIM	60.0
AACOMP	81.9
Seqdif (SeqID)	48.9 (WP_310064357.1)
Structdif (F-Target)	14.8 (4qgm A)

ProtNLM

Name	Score
1.13.11.54	0.125
Fe-ARD	0.121
ARD	0.110
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	0.107
ARD'	0.094
Acireductone dioxygenase (Ni(2+)-requiring)	0.088