MYFE0

Prompt

1.6.3.2

Oxidoreductases. Acting on NADH or NADPH. With oxygen as acceptor. NAD(P)H oxidase (H2O-forming).

AI Generated Sequence

500 AAs

MLLLPVCRNLISLLRGSSSCSSSALRRQLDKNITFHKLVAWMIAVNTAIHTVAHLFNVERYVNSRQVDYSGLPAVLSNLGRDPNETYLNPIRTFGNPTGTVFVTTAPGITGYVITICLLLIITSSTEKIRRSSYEVFWYTHHLFVVIFIGLMIHGAGRIVRGQTPESLKVHNPVFCDKYHSWEGKIDNCPIPQFAGNPEMTWKWVIGPMFLYLCERLVRFWRSQQKVVITKVVMHPSKVLELQMKKKGFKMEPGQYIFINCPAISKLEWHPFTLTSAPEEDYFSVHIRIVGDWTEKLFKACGLDEKQFKDWKLPRVAVDGPFGTASEDVFSYEVSMLVGAGIGVTPFASILKSIWYRYCNEQPTLRLKKVYFYWLCRDTHAFEWFADLLQSLETQMEERGKANFLSYYIYLTGWDESQAHFIAMHHDEKDVITGLKQKTLFGRPNWNEEFKTIANNHPSTNIGVFLCGPKALAKTLSKHCRMNYSIDPRGVKFHYNKENF

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	85.2
NLMSIM	70.0
AACOMP	93.4
Seqdif (SeqID)	26.1 (XP_019488069.1)
Structdif (F-Target)	19.6 (8gz3 B)

ProtNLM

Name	Score
Cytochrome b-245 heavy chain	0.370
NADPH oxidase 3	0.194
FAD-binding FR-type domain-containing protein	0.142
Cytochrome b-245 heavy chain-like	0.110
NADPH oxidase 1	0.036
Cytochrome b-245, beta polypeptide (chronic granulomatous disease)	0.031