MYDPW

Prompt

1.1.1.388

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. glucose-6-phosphate dehydrogenase (NAD(+)).

AI Generated Sequence

500 AAs

MTDPRPPPPPGCFVVFGASGDLTRRLLLPALYNLFRDGLLPEGARILGVAREEMTDEGFRARVEEGIREFAREGEVDEAVWERFAAGISYVSGDLDDPAGFARLAELLDGRGERGNRVFYLATAPSLFGPVIEGLAAAGLVDEGWRRVVVEKPFGRDLASARALNDAVHRHFDERQIYRIDHYLGKETVQNLMALRFANALFEPLWNRNHIDHVQITAAETVGVEGRGGFYDGTGALRDMVPNHLFQLLCLVAMEPPVSMDADAVRNEKVKVLRALRPITDEDAARHTVRGQYAAGAVDGRAVPGYLEEEGVAPDSRTETFVALKLHIDNWRWAGVPFYLRTGKRMPVRRTEIAVQFRPAPHAIFGDTDAERFGPNWLVIRIQPDEGVSLRMDIKVPGPGMRVRPVNMDFSYADLFEAPPSIAYETLLYDCLIGDQTLFQRADAVEAGWAWAEPILEAWAADPPPPIEGYAAGSWGPAAADALIARDGRAWRRPDDPGRR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.2
NLMSIM	70.0
AACOMP	90.6
Seqdif (SeqID)	39.3 (HVJ52531.1)
Structdif (F-Target)	4.0 (7xhl H)

ProtNLM

Name	Score
Glucose-6-phosphate 1-dehydrogenase	0.381
1.1.1.49	0.346
G6PD	0.268
Glucose-6-phosphate dehydrogenase	0.001
Isocitrate dehydrogenase [NADP]	0.000
Glucose-6-phosphate 1-dehydrogenase 1	0.000