MY7MS

Prompt

1.1.1.383

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. ketol-acid reductoisomerase [NAD(P)(+)].

AI Generated Sequence

513 AAs

MAKIYYDKDADLSLIKGKKVAIIGYGSQGHAHALNLRDSGVDVVVGLREGSKSWAKAEADGLKVMSVAEATAWADVIMILAPDEHQADIYKEHIEPNLKAGAALAFAHGFNIHFGQIEVPADVDVFMIAPKGPGHTVRSEYVQGRGVPCLIAVEQDASGNAKDLALSYASAIGGGRAGVIKTNFNEETETDLFGEQAVLCGGLTALVQAGFETLVEAGYAPEMAYFECLHEVKLIVDLMYEGGIAKMNYSISNTAEYGDYVTGPRIINEETKAEMKRVLADIQDGKFARDFILENKAGQPEFKATRRAAEEHQIEVTGKELRSLMPWIGGNVIDKIENLNAQAVPVFEGDQKVLVDTIAKYRNGELLGPEQLTEVAKMTKAMMAGIKALEEYSEVRVLYSYITRRGTYVENVNKVGTAYKENGELVEVDEAGNMAGMYRRDAQEALEFLEAQVGAAEKIMQVLSGKQVLVDNGSVKYLTDEMFAEGGKFGGINMYAGATMNAGFKEAMQQAMK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	71.1
NLMSIM	70.0
AACOMP	91.6
Seqdif (SeqID)	25.1 (WP_028965304.1)
Structdif (F-Target)	2.2 (5yeq B)

ProtNLM

Name	Score
AHIR	0.218
Alpha-keto-beta-hydroxylacyl reductoisomerase	0.188
Ketol-acid reductoisomerase (NADP(+))	0.166
1.1.1.86	0.143
KARI	0.123
Acetohydroxy-acid isomeroreductase	0.117