MXV9P

Prompt

1.1.1.351

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating].

AI Generated Sequence

500 AAs

MSKKIGIIGALGMGSNLALNMIEKGFPVVAFNRTVEKVDELVKKNPEGKTLVGVYSLEEFVSKLEKPRKIWIMVKAGKPTDQVIEQLKPLLEKGDIIIDGGNSHYEDTIRRVEELKKKGIHFIGTGVSGGEEGARNGPSMMPGGSEEAYELVKPIFQKIAAKVEDGEPCTDWVGPNGAGHFVKMVHNGIEYGDMQLICEGYHLLKDVLGLSNEEMHKVFDEWNKGELDSYLIEITRDIFLKKDEDGKYLVDKILDTAGQKGTGKWTGINALDLGVPVTLITESVFARCLSSLKDERVQASKLFPGPIKPFKGDKKEFIEDLRKALYFSKICSYAQGFMQLRKASEEYNWDLNYGEIAKMWRGGCIIRAQFLRKIKDAYDENPELQNLLLAPFFKDAVDNAQPAWRKVVSIAVQAGIPTPGFSAALAYFDGYRTERLPANLLQAQRDYFGAHTYERLDKPRGSFHTEWNGSGGEKVNASTYNHDFHDIYQVEKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	88.3
NLMSIM	85.0
AACOMP	91.5
Seqdif (SeqID)	30.5 (HHV96755.1)
Structdif (F-Target)	1.8 (7cb2 A)

ProtNLM

Name	Score
1.1.1.44	0.624
6-phosphogluconate dehydrogenase, decarboxylating	0.366
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	0.002
NADP-dependent phosphogluconate dehydrogenase	0.002
6PGD domain-containing protein	0.001
Decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase	0.001