MXURH

Prompt

1.3.1.15

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. dihydroorotate dehydrogenase (NADP(+)).

AI Generated Sequence

392 AAs

MLYPLLRPLLFRLDPERAHGLTLRALRRALGTPLLRLLRPPAPALPVTVMGLTFPNPLGLAAGLDKNGEAIDALGAMGFGFVEVGTVTPRPQPGNDRPRLFRLPEDAALINRMGFNNLGVDHLVERLARARYRGVLGINIGKNKDTPNERAVDDYLICMERVYPHAGYIAVNISSPNTPGLRSLQHGEALDALLAALRARQAELAARHGRRVPLAVKIAPDLTEAELEAVAAALLAHGIDGVIATNTTLDRAGVAGLPHAGEAGGLSGAPLFARSTEVLRRLRARLGGALPIIGVGGIDSGAAARAKLAAGADLVQVYSGLVYRGPGLIGECVAALAAARAAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.4
NLMSIM	60.0
AACOMP	81.7
Seqdif (SeqID)	29.5 (WP_166931974.1)
Structdif (F-Target)	2.4 (7t6h B)

ProtNLM

Name	Score
DHOdehase	0.214
DHODase	0.183
1.3.5.2	0.175
Dihydroorotate oxidase	0.157
DHOD	0.141
Dihydroorotate dehydrogenase (quinone)	0.123