MXT7P

Prompt

1.13.11.2

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. catechol 2,3-dioxygenase.

AI Generated Sequence

307 AAs
MPKGVMRPGHVQLRVLDMATALEHYTDVLGMIETERDQEGRVYLKAWTEVDHFSVVLREADEPGMDYMAFKVADEDALKQLEADLTAYGVEIEWLPAGELPRCGRRIRFHAPSGHHFELYADKEYTGKWGVTEANPEAWPRDLRGMAPTRFDHCLLYGDDLPATYKLFTEVLGFYLTEQVVDEDGVRIAQFLTCSAKAHDVAFIHHEPKGRLHHVAFFLETWHDVLRAADLISMTDTSIDIGPTRHGLTRGQTIYFFDPSGNRNEVFCGGNYTYPDHKPVTWAEDLGKRAIFYHDRALNERFMTVLT

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT87.0
NLMSIM95.0
AACOMP92.2
Seqdif (SeqID)17.9 (WP_009397178.1)
Structdif (F-Target)5.1 (1mpy D)

ProtNLM

NameScore
1.13.11.20.320
Catechol 2,3-dioxygenase0.238
CatO2ase0.236
Metapyrocatechase0.186
3,4-dihydroxyphenylacetate 2,3-dioxygenase0.001
Manganese-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase0.000
Designed by MP, using an AMD MI250 GPU