MXPDV

Prompt

1.14.13.51

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. 6-oxocineole dehydrogenase.

AI Generated Sequence

432 AAs

MSDLLSKLKKKPKIVVGGGWGAFNLAKKLNKKDYDITLVDKNNYHLFTPMLPEVATGTLESFSSIEPYLRIVHKRHNNFRLQAEVKSIDREKKTILCEPVEGEELTYDYLVMAAVGASTNFHGTKGLEHACMFLKSIEDAQRIHRQILNAFEKASYTLSDEEKRKALTFSIVGGGPTGVELAGELHDFVRELSDKYGKINDLNLKITLIEQGDRILPTFDKKISTYAEKELTKLGVDILLNTRVKEVDKDHVFTKDGTEIPCDMTVWASGIKSPPFLKSLGQLEMNRRNQLVVNPLQLTRGFDNIYAIGDCANVQDKNTKGFPPTAQAVAQQGGKYLAKNILKLKNGKELKPFKYHDFGSLASIGRNSAVAQLMGKFNRGFFAWMWMRAHVFYLSVSFRNKVRVLGDWTKTLMFGRDSLRTIIPPDKSKVHL

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	89.3
NLMSIM	70.0
AACOMP	92.9
Seqdif (SeqID)	57.7 (MCL4539504.1)
Structdif (F-Target)	7.5 (5na4 A)

ProtNLM

Name	Score
NADH dehydrogenase	0.325
NAD(P)/FAD-dependent oxidoreductase	0.243
FAD-dependent oxidoreductase	0.212
1.6.99.3	0.071
NADH dehydrogenase FAD-containing subunit	0.046
Pyr_redox_2 domain-containing protein	0.018