MXEAI

Prompt

1.14.99.29

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. deoxyhypusine monooxygenase.

AI Generated Sequence

299 AAs
MSDETISETIETLRKVLVDESEPLARRFRALFSLKHLAGQPEAIDAIAAAFTDPSALLKHELAYVLGQMRNPAAIPTLEKVLKDTEQEPMVRHEAAEGLGAIGYAESLDILRDYLKDDPVEVVRQTCEIAIDRIQWENSGEKAKEKLTPSDYTSIDPAPPMAEEASVPELRKTLLDTSKPLFERYRAMFALRDTASEEAVAALAKGLADPSALFRHEIAYVFGQLCHPASVPALTEVLSNRSEAPMVRHECAEALGSIADPECVETLKKFALDPEQVVRDSCEVALDMYEYEKSGELAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT88.7
NLMSIM80.0
AACOMP90.8
Seqdif (SeqID)31.8 (XP_043142102.1)
Structdif (F-Target)4.4 (4d4z A)

ProtNLM

NameScore
Deoxyhypusine monooxygenase0.287
DOHH0.237
Deoxyhypusine dioxygenase0.213
1.14.99.290.143
Deoxyhypusine hydroxylase0.105
Deoxyhypusine oxygenase0.001
Designed by MP, using an AMD MI250 GPU