MX6VR

Prompt

2.5.1.60

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. protein geranylgeranyltransferase type II.

AI Generated Sequence

566 AAs

MHGRLKVKTSEEQAEAKRLEREQKLKIYQSATRAVFQKRQAGELDESVLELTSQILGTNPDFATLWNYRREVIQHLEAQKSPEELAALVKAELGFTESCLRVNPKSYGTWHHRCWVLGRLPEPNWARELELCARFLELDERNFHCWDYRRFVATQAAVPPAEEFAFTDSLITRNFSNYSSWHYRSCLLPQLHPQPDSGPQGRLPERVLLKEYELVQNAFFTDPNDQSAWFYHRWLLGRADPQDLARCLHVSRDEALVTVSFSRPVVVGSGTEILLLMVDESPLAVEWRTPDGRNRPSHVWLCDLPAISLNDQLPQTFRVIWATGDARQKECVLLKGRQEGWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTIILLMRALDPLGYEKETLQYFQTLKAVDPMRAAYLDDLRSKFMLENSVLKMEYAEVRVLHLAHKDLTVLCHLDQLLLVTHLDLSRNRLRTLPPAFAMLRCLEVLQANDNAIESLDGVTNLPRLQELMLCNNRLQQPATLQPLASCPRLVTLNLQGNPLCQAAGILSELAELLPSVSSIL

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	82.1
NLMSIM	95.0
AACOMP	90.6
Seqdif (SeqID)	7.4 (XP_003901688.1)
Structdif (F-Target)	6.5 (1ltx A)

ProtNLM

Name	Score
Geranylgeranyl transferase type II subunit alpha	0.369
Geranylgeranyl transferase type-2 subunit alpha	0.320
2.5.1.60	0.250
Rab geranyl-geranyltransferase subunit alpha	0.020
Rab geranylgeranyltransferase subunit alpha	0.007
Rab GGTase alpha	0.005