MX53F

Prompt

6.2.1.54

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. D-alanine--[D-alanyl-carrier protein] ligase.

AI Generated Sequence

499 AAs

MKTLIDAIDAWAAAQPDRPAYVHGGEALTYGQLAADSDALAHALRGLGLPRDRPVLVYGHMHPEMLIAFLGCVKAGHAYVPVDTHLPADRVARIVAAAGAALLLAAGALPVDLPGVPVLTLDDLAALFAGGAPPAPAAAVRGDDTFYIIYTSGSTGTPKGVQISHANLVSFTRWMLADFALGGGQRFLAQAPFSFDLSVMDLWPALASGGTLCALDKAMTADFKALFAALPALPLQVWVSTPSFADLCLLDAAFSAAAHPALTRFLFCGEVLAHATARALLARFPGARIFNTYGPTEATVAVTAVQVTAAVLDAHPRLPVGYARPDARLLLLDDGAPLPAGERGELIVAGPSVSKGYLGNAEKTAAAFFTLDGRPAYRTGDAGRLADGLLLYAGRLDFQVKLHGYRIELEEIEAHLRAVPGVAGAVVVPLVRPGDRVTHLLAYVVPQAHAFELTAAIKAELRARLPAYMIPRRFVYRAALPLTPNGKVDRKGLLAEVNA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	92.7
NLMSIM	60.0
AACOMP	87.2
Seqdif (SeqID)	41.6 (WP_306692138.1)
Structdif (F-Target)	4.8 (3lgx B)

ProtNLM

Name	Score
D-alanine--poly(phosphoribitol) ligase subunit 1	0.271
D-alanine--D-alanyl carrier protein ligase	0.234
D-alanine-activating enzyme	0.177
DAE	0.119
6.2.1.54	0.118
DCL	0.058