MX4WU

Prompt

6.2.1.44

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. 3-(methylthio)propionyl--CoA ligase.

AI Generated Sequence

499 AAs

MSEYERVYRESLAEDPEAFWAEQARDLHWHRPFDRVLDSDAPFYAKWFVGGKTNLCYNAVDRHVAARGDQRALIYESPTEGTERTFTYAELHAEVNRMAGVLRSLGVEKGDRVILYMPMIPEAFSAMLACARIGAIHSVVFGGFAAESLAARIHDAGPKLVITASCGERGGKVVPYKPLVDEALKLSHHAPKVVIVHDRGLQDAPWADGRDVDWHALVAEAAPVACEWVESEDPLYILYTSGTTGKPKGVQRDTGGYAVALAASMKHIFDIRPGDVFWTASDVGWVVGHSYIVYGPLLAGITTVLYEGVPGTRPDAGRWWEIVDHHKVTTMFTAPTAIRALRKDGPEHVAKGYDLSSLRTLFLAGERLDEPTLEWVHEGIGKPVIDNYWQTETGWPIMATPIGAAELPKPGSAGVPVPGYDVRLVDENGEECPEGEAGNIVIAQPLPPGCMRTLWGDHERFVRTYWSQFPGYYVDTGDGCRDEDGYFWVMGRTDDVINV

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	84.2
NLMSIM	70.0
AACOMP	92.5
Seqdif (SeqID)	36.8 (TWG86710.1)
Structdif (F-Target)	5.5 (5vpv C)

ProtNLM

Name	Score
Propionyl-CoA synthetase	0.377
6.2.1.17	0.205
Propionate--CoA ligase	0.196
Acetyl-coenzyme A synthetase	0.067
6.2.1.1	0.057
Acetyl-CoA synthetase	0.028