MWZ9G

Prompt

1.13.11.17

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. indole 2,3-dioxygenase.

AI Generated Sequence

433 AAs

MLPLPPLPDFGISERHGFLPDRPPLERLPDPYYNKWEAIVANLPPLISEGRLRGVIDRLPVLSTQHLHHSEEWRRAHYVLGFMAHGYVWDGDVPERVLPASISVPLVEIAEHLGLPPVTTYASVCLWNWKPIDGDPEIFDLNNLAVINTFTGSLDESWFYLVSVAIEARAGPILPLMLDAIAAAREDRAAVTRCLREFARALGDIGTLLERMHESCDPHVFYHRIRPFLAGSKNMAEAGLPNGVIYDGTDQEPTYRQLSGGSNAQSSLIQFFDIVLGIEHRPMTKGEDSKESKSGSPPPPPPPFHNFIHEMRRYMPGPHRRFLEHVASVPNVRAYVERSQNDSRLCAADYNCLAMLRAFRDRHWIQIVARYIVRQSQRSRPSHGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.1
NLMSIM	85.0
AACOMP	88.3
Seqdif (SeqID)	32.2 (XP_009251759.1)
Structdif (F-Target)	6.1 (7rrb A)

ProtNLM

Name	Score
Indoleamine 2,3-dioxygenase	0.323
Indoleamine 2,3-dioxygenase subfamily	0.254
Indoleamine 2,3-dioxygenase family protein	0.116
Indoleamine 2,3-dioxygenase alpha type	0.099
Indoleamine 2,3-dioxygenase beta type	0.019
Indoleamine 2,3-dioxygenase pyrrole 2,3-dioxygenase	0.019