MWTBF

Prompt

1.2.1.36

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. retinal dehydrogenase.

AI Generated Sequence

495 AAs

MPLPPHRILLNNGKNFIGGWYGTASSKKPPTVNPATVEAIEVGYRHCDTADVYNEAVEVGRAVRAGWKDGTVKRERILYISKLWEDHHRPEELAAASEKDLGKLQLDVYVDLYLHISPFRFFAGEADKPYHGKTIPIDPHDFHYTRWEMGVCVGGIWPNFPLGMFFNRKLAPILANGCTVVKPATQTETCPLYLQEKLLEACFPPKGVLNVTYGLPGTGDAWSKHPDVDKILFTGSTTVGLIHKKYGKASNLIRLTLELGGKSPVIVSKDAELIEENVQVFDFSFFNQGQVCCAVNSRIYVHSVYDEFVEKLVEKAKSLKLGDPFDPGTKMGPQVNQKHYEKVLSYIKIGKEKGATLECGGERGLDKGYFIQPTVFTNVQDDMRIAKEEIFGPVLPIMKFKTEEEVIARANDTTYGLAAGVFTKDLNKAHRVAAELEAGTVWVNCYSILNAQRPFGGFKNSGIGRELGYYGLEHYTQTKTVHVNIPKKNWGYLEE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	76.7
NLMSIM	85.0
AACOMP	92.9
Seqdif (SeqID)	48.5 (XP_050843194.1)
Structdif (F-Target)	12.3 (4ywv B)

ProtNLM

Name	Score
Aldehyde dehydrogenase	0.358
Aldedh domain-containing protein	0.202
Aldehyde dehydrogenase (NAD+)	0.083
Aldehyde dehydrogenase, mitochondrial	0.083
Aldehyde/histidinol dehydrogenase	0.064
Betaine aldehyde dehydrogenase	0.020