MWRU6

Prompt

1.13.11.53

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. acireductone dioxygenase (Ni(2+)-requiring).

AI Generated Sequence

182 AAs

MSRLTIYDDTNPEKPVLDTTDLETIAAELDKIGVRFERWEADQPVEEGASQEEILAAYKAEIDKLSAEKGFKTWDVIKINPDNPKKEELRAKFLDEHTHKEDEVRFFVEGRGLFTLHVDGEVYEVLCEKGDLISVPAGTIHWFDMGEKPHFVAIRLFTNPEGWVAHFTGDDIASKFPRLDEE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.2
NLMSIM	85.0
AACOMP	89.3
Seqdif (SeqID)	31.5 (HSC85408.1)
Structdif (F-Target)	12.8 (4qgm A)

ProtNLM

Name	Score
1.13.11.54	0.117
ARD'	0.110
Acireductone dioxygenase (Ni(2+)-requiring)	0.102
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	0.098
ARD	0.098
Fe-ARD	0.097