MWHQ9

Prompt

1.5.7.1

Oxidoreductases. Acting on the CH-NH group of donors. With an iron-sulfur protein as acceptor. methylenetetrahydrofolate reductase (ferredoxin).

AI Generated Sequence

343 AAs
MKITDLIAAGKTAVSFEFFPPKTEAGFENIYRTIDELMEWDPDFISVTYGAGGSTRERTHEIAARIQKKYTVPAMAHLTCVGATKEEINDVLDRYWDAGIHNILALRGDPPKGEARFVPTPDGFAYASELVELIQGMAPGFCIGVAGYPEGHPESPNLETDIEHLKRKVDAGADYAITQLFFDNDDFYRFVDRVRAAGITVPIIPGIMPITNFAQLKRMASLCGASLPAALAARLEGAKDDPAAVRQVGIAHATEQCRDLLDAGVRHFHFYTMNKSALTYAICRNLGIRPRQPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT93.6
NLMSIM85.0
AACOMP82.9
Seqdif (SeqID)42.7 (MDB5355075.1)
Structdif (F-Target)3.3 (1v93 A)

ProtNLM

NameScore
1.5.1.200.501
Methylenetetrahydrofolate reductase0.473
Methylenetetrahydrofolate reductase (NAD(P)H)0.018
Methylenetetrahydrofolate reductase [NAD(P)H]0.002
5,10-methylenetetrahydrofolate reductase0.001
Methylenetetrahydrofolate reductase,0.000
Designed by MP, using an AMD MI250 GPU