MWGVF

Prompt

3.5.2.17

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amides. hydroxyisourate hydrolase.

AI Generated Sequence

118 AAs
MGGPLTTHVLDTARGCPAAGLAVELYRLADGARERLAAGVTNADGRVDGPLLPGAALAPGTYRLRFDTGAYFAARGVALPEPAFLDVVPVRFGIADAAQHYHVPLLLSPFGYSTYRGS

Ligand/Cofactor

hydroxyisourate

C12=NC(=NC1(C(=O)NC(=O)N2)O)[O-]

Validation Metrics

PLDDT89.0
NLMSIM95.0
AACOMP85.8
Seqdif (SeqID)26.5 (WP_251779858.1)
Structdif (F-Target)3.9 (4q14 B)

ProtNLM

NameScore
HIUHase0.277
3.5.2.170.251
HIU hydrolase0.231
5-hydroxyisourate hydrolase0.231
Hydroxyisourate hydrolase0.003
TR_THY domain-containing protein0.000
Designed by MP, using an AMD MI250 GPU