MW8OQ

Prompt

2.5.1.60

Transferases. Transferring alkyl or aryl groups, other than methyl groups. Transferring alkyl or aryl groups, other than methyl groups. protein geranylgeranyltransferase type II.

AI Generated Sequence

500 AAs

MHGRLKVKTTEEQAEAKRLEREQKLKLYQALTETVFQKRAAGELDEAVLELTSQILSANPDFATLWNYRREILQRLEAQKSPEELAALVKSELGFLESCLRVNPKSYGTWHHRCWLLSRLPEPNWARELEVCDRFLEADERNFHCWDYRRFVATQAAVPAEEELAFTDSLITRNFSNYSSWHYRSTLLPQLHPQPDSPQGRLPEDVLLKEFELVQNAIFTDPNDQSWLFYHRWLLGRADPQDALRCLHVSRDEACLTVSFSRPLVVGSRMEILLMVDDSPLVIEWRTPRGNRNPSHVWLCDLPAAGLNDGQPHTFRVIWTAGDAQRECVLLKGAQEGWCRDSATDEQLFRCELSVEKSTVLQSELESCKELQELEPENKWCLLTTILLMRALDPLLYEKETLQYFQTLKAVDPMRAAYLDDLRSKFILENSVLKMEYAEVRVLHLAHKDLTVLCHLDQLLLVTHLDLSHNRLRTLPPALAALRCLEVLQADNGAIESVDG

Ligand/Cofactor

PLP

CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O

Validation Metrics

PLDDT	84.5
NLMSIM	95.0
AACOMP	90.4
Seqdif (SeqID)	9.7 (XP_025248896.1)
Structdif (F-Target)	9.4 (1ltx A)

ProtNLM

Name	Score
Geranylgeranyl transferase type II subunit alpha	0.370
Geranylgeranyl transferase type-2 subunit alpha	0.308
2.5.1.60	0.218
Rab geranyl-geranyltransferase subunit alpha	0.039
Rab geranylgeranyltransferase subunit alpha	0.013
Rab GGTase alpha	0.011