MW7SV

Prompt

6.2.1.45

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. E1 ubiquitin-activating enzyme.

AI Generated Sequence

500 AAs

MDENEIDESLYSRQLYVLGHEAMKRMATSNVLIVGLRGLGVEIAKNIALAGVKSVTLYDPKPVAISDLSTQFFLRPEDVGKPRAEAVPRLAELNAYVPVTVHTGPLTEDLSQLKQYQVVVLTETPLKEQLAINDFCHSKNIYFIIADTRGLFGSVFCDFGEKFTVGDPTGETPLSMIVAGITDENGIVTCLDETRHGLEDGDYVTFSEVQGMTALNGCEPRKVTVLGPYTFSIGDTSGLGTYQRGGIFTQVKMPKFINFKPLSAQLKEPEFLIYDFAKFDRPQQLHVGFQALHKFAETHGRLPRPWNEEDAQEVLALAKNFAAETGLKVELDEKLIKELSYQARGDLSPMAAFFGGLAAQEVLKAVSGKFTPIKQWLYFDSLESLPTGTARTEEDCKPRGSRYDGQIAVFGKEFQEKIANLRQFLVGAGAIGCEMLKNWAMIGLGTGPEGKITVTDMDTIEKSNLNRQFLFRPWDVGKLKSECAAAAVQRMNPDLKIDIT

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	93.7
NLMSIM	95.0
AACOMP	95.4
Seqdif (SeqID)	22.2 (UZP45689.1)
Structdif (F-Target)	4.8 (6nya A)

ProtNLM

Name	Score
Ubiquitin-activating enzyme E1	0.224
UBA_e1_C domain-containing protein	0.212
Ubiquitin-activating emzyme E1	0.174
Ubiquitin-activating enzyme E1 1	0.091
Ubiquitin activating enzyme	0.038
Ubiquitin-like modifier-activating enzyme 1	0.022