MW2YP

Prompt

1.2.3.8

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With oxygen as acceptor. pyridoxal oxidase.

AI Generated Sequence

213 AAs
MTDLADLRRDYSRAGLDRADLGADPWAQFERWFAEAVAAEVNEPNAMTVATVGPDGRPSVRMVLLKGLDERGFVFYTNYESRKGRELAANPHAALLFHWKELRRQVRIEGRVEKVSAEESDAYFATRPRGSRIGAWASEQSRPIASRFALEARVAETAARFGIGEVPRPPHWGGYRIRPVRIEFWQGRPSRLHDRILYTRDAAGGWTRERLAP

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT94.0
NLMSIM70.0
AACOMP88.3
Seqdif (SeqID)27.9 (WP_063550347.1)
Structdif (F-Target)3.0 (1jnw 2)

ProtNLM

NameScore
PNP/PMP oxidase0.239
PNPOx0.214
Pyridoxine/pyridoxamine 5'-phosphate oxidase0.214
Pyridoxal 5'-phosphate synthase0.209
1.4.3.50.115
Pyridoxamine 5'-phosphate oxidase0.004
Designed by MP, using an AMD MI250 GPU