MW1SG

Prompt

5.4.99.13

Isomerases. Intramolecular transferases. Transferring other groups. isobutyryl-CoA mutase.

AI Generated Sequence

769 AAs

MTDLSKYTPKNHIRIVTAASLFDGHDASINIMRRIIQSTGVEVIHLGHNRSVEEVVNAAIQEDVQGIAMSSYQGGHIEYFKYMYDLLKEKGAGHIKIFGGGGGVILPSEIKELHDYGIARIYSPEDGRKMGLQGMINDMVQRSDFPTGKELNGELDKISGKDVRAIARLISLAENFPEEKASVEAALKEKAAAAKKAPVLGITGTGGAGKSSLTDELVRRFLDVFPDKTIAILSVDPSKRKTGGALLGDRIRMNAINNPRVYMRSLATRQSNLELSKHVADAIDVVKAAGYDLIILETSGIGQGDTEITEHSDVSMYVMTPEFGAPTQLEKIDMLDFADLVAINKFDKRGALDALRDVQKQYQRNHLLWDKPDEEMPVYGTIASQFNDPGTNTLYAAIMDKINEKTKANLWSTFEITDKVEEKNFIIPGDRTYYLSEITENVRNYNKTAEQSAEVARKLYQLHTTMESVKSNLPADEKALDALETIYDRVKAELDLENKEILENWEEKKAEYKGDEFFTKVRDKEIRTEIKTESLSGTKIPKVALPKYEDWGDILRWCMKENAPGEFYPTAGVFPFKREGEDPTRMFAGEGGPERTNRRFHYLSKDMPAKRLSTAFDSVTLYGEDPDYRPDIFGKIGNSGVSICCLEDMKKLYSGFNLCAPMTSVSMTINGPAPMILAMFMNTAIDQQVEKFIEENGRELTEEEYAKIRAVTLQNVRGTQYADILKEDQGLNTICFMTEFTLRMVGDIQEYYIDKRVRNLYSVSISGYH

Ligand/Cofactor

acetyl-CoA

CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O

Validation Metrics

PLDDT	74.8
NLMSIM	70.0
AACOMP	93.9
Seqdif (SeqID)	32.1 (WP_090261287.1)
Structdif (F-Target)	32.7 (4xc8 A)

ProtNLM

Name	Score
Fused isobutyryl-CoA mutase	0.260
Isobutyryl-CoA mutase	0.148
5.4.99.13	0.135
ICM	0.129
P-loop GTPase	0.123
3.6.5.-	0.097