MVWPU

Prompt

1.2.1.84

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. alcohol-forming fatty acyl-CoA reductase.

AI Generated Sequence

515 AAs

MTQLQQLYQGKTILITGATGFLGKVLLEKLLRQCPNVKRVYLLIRAPKGQTAEQRVQEFVNGKLFDRLRERHPDFIEKITPIAGDITNPDLGLNEADIDIITEETNIIIHCAATVTFNEPLRDALQVNTLGTLHVLAFAKKMNKLKLLLHVSTAYVNCLKKIGEEVYETPMHPEVRIIDTLEWMDDVLVNIGLPRKLDGWPNTYVFTKALGEHMVQQYGGTLPLAIIRPSIVGASFKEPFPGWIDGFNTSIGFIIAAGKGLRTLMRANMNNLADLVPVDMVVNMILAAAWHAVGNRESPTVYNVTSGIRNPFGWSELYLYINNYFNRNPLANGVFRPRFEFTNNLQLHYWTVINHKLPAALFDRLLRLTGKSQPRMIKYIGHLARMATYEPYTFSNFRFTDTNTARLAALMQTPEKKFNFHVDAHIDWADYFENHIPGIKKYVLKEDMSGLPAARKWINRLNRIRYGINFTGIDFIIWRIFIAQGQMAQNIWFVGVMNYYKFLGPYFASSSTMRY

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.5
NLMSIM	85.0
AACOMP	92.9
Seqdif (SeqID)	46.8 (XP_059960243.1)
Structdif (F-Target)	14.6 (7eoz B)

ProtNLM

Name	Score
Fatty acyl-CoA reductase	0.511
1.2.1.84	0.471
Fatty acyl-CoA reductase 1	0.004
PlsC domain-containing protein	0.001
Fatty acyl-CoA reductase 2	0.001
Long-chain-fatty-acid--CoA ligase	0.001