MVMGF

Prompt

1.1.1.277

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3beta-hydroxy-5beta-steroid dehydrogenase.

AI Generated Sequence

392 AAs

MTDRVLVTGGCGFLGRHLVRRLLDEGHEVRVLDRVPEPERLAALGVRHYQADLADPAAVAAALAGADAVVHTASPDFWSGIDPRRLHEVNVDGTRNVLAAARAAGVRRLVYTSSPGVVFDGVDDVLGADESLPYAPHRPDPYAETKAIAEALVLAANGDGLVTCALRPAGIFGPGDRQLVPRLAAALRAGSLKFQIGDNDNLVDWTYVDNAAQAHLLAAERLAGDGAADVAGQAFFITNGEPVEFDDFARILAAEGGRDPRRIRLPASLMPLAHLLAETWSFLLPYGFRPPALTRYRVYGLCSTRHYSCDKARERLGYAPVVGWEEGLRRTAEWFPLHAERRAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.8
NLMSIM	70.0
AACOMP	81.4
Seqdif (SeqID)	52.1 (XP_059285364.1)
Structdif (F-Target)	11.2 (3aw9 2)

ProtNLM

Name	Score
3Beta_HSD domain-containing protein	0.289
NAD-dependent epimerase/dehydratase family protein	0.065
NAD(P)-dependent oxidoreductase	0.064
NAD(P)-dependent steroid dehydrogenase-like protein	0.061
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating	0.039
3-beta hydroxysteroid dehydrogenase	0.034