MVH3F

Prompt

1.1.1.270

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3beta-hydroxysteroid 3-dehydrogenase.

AI Generated Sequence

395 AAs

MEHLEENLLSLTLLLLLEVAAFTGVLLYEVVPYKGYRHELSRTGWKVPCRCAWFLQELPSFLVPLALLLAHAKGSLSLPNRCLLGLFFCHVYQRSLIYPLLIRGGKTPLPVTFALMAFFCCYNGYLQGRYLSHVAEYPESWVTDIRFISGVLLHLLGMLVNIHSDHILRNLRKPGETGYKIPRGGLFEYVSGANYFGEIVEWCGFALCTWSVAGLAFAFLTTVNLGPRAAEHHRYWLKKFTDYPKDRKELIPMFIILPTFPLLLPFTLLNTQVFAFLSRWLGGWSRSESEGTYSNWKYPLRPLSIPLLPPKTKLRFLLFLLGSVMYGESVYRWMRRSRSSDSSMQSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	72.9
NLMSIM	60.0
AACOMP	84.2
Seqdif (SeqID)	40.3 (XP_010871531.1)
Structdif (F-Target)	6.9 (7bw1 A)

ProtNLM

Name	Score
S5A_REDUCTASE domain-containing protein	0.251
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+))	0.231
3-oxo-5-alpha-steroid 4-dehydrogenase	0.226
1.3.1.22	0.212
SR type 1	0.018
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0.013