MVB5O

Prompt

6.3.2.13

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase.

AI Generated Sequence

500 AAs

MKLKELIKKIPYHEIHLNEIEITGISYDSRKVKKGDLFFCKGKTVFDHKFYKKAIDKGAKAILAEKELDLDLPLIIVNDYHKAMALLASAFYDFPSKKLKIIGITGTKGKTTTAYFTYKILKDYGYKTALFSTGRDKIGDEKIKASHLTPGALDLFKSFREAVDNKCEYAVMEVSSHAIKQHRVYGIDFDIGVFLNLTQDHIEYHKTFENYFKAKGLFFTDLNNANFIFNLDHPFSKFYKDNTKAKTITYGINENADYHAKNIELSLDGISFKLNTPKMTIDFKSKLIGDFNIYNALAAIGVCGLLGVELEDIKKGIENFTAVPGRMEVVQTKQNFAVIVDYAHTPDSLEKLFESVKEIAPNKLICVFGCGGDRDISKRPIMAKIASEYADIAILTSDNPRSEDPLAIIDDIMKGIDKNKNVKVILDRKEAIKKAIEIAKENDIVLIAGKGHETYQIIKDVKVPFDDREVVKEYFEKKGGKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	95.3
NLMSIM	60.0
AACOMP	85.2
Seqdif (SeqID)	50.0 (WP_092347973.1)
Structdif (F-Target)	5.0 (4bub A)

ProtNLM

Name	Score
UDP-MurNAc-tripeptide synthetase	0.207
Meso-diaminopimelate-adding enzyme	0.189
6.3.2.13	0.165
UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase	0.137
UDP-N-acetylmuramyl-tripeptide synthetase	0.109
Meso-A2pm-adding enzyme	0.097