MV586

Prompt

4.2.1.76

Lyases. Carbon-oxygen lyases. Hydro-lyases. UDP-glucose 4,6-dehydratase.

AI Generated Sequence

652 AAs

MATYAPKNILITGAAGFIASHVANRLVRSYPEYKIVVLDKLDYCSNLKNLNPSKSSPNYKFVKGDIASADLVNYLLITESIDTIMHFAAETHVDNSFGNSFEFTKNNIYGTHVLLEACKVTGQIKRFIHVSTDEVYGETDEDAVVGNHEASQLLPTNPYSATKAGAEMLVMAYGRSYGLPVITTRGNNVYGPNQFPEKLIPKFILLAMQGKPLPIHGDGSNVRSYLYCEDVAEAFEVILHKGEVGHVYNIGTKRERRVLDVARDICKLFGKEPESIIKFVENRPFNDQRYFLDDQKLKNLGWSERTTWEEGIRKTMEWYTQNPNWWGDVSGALLPHPRMLMPGGDRLFGYGEEKTGGENATQMVVPTPTIKPAAPAAAAAAPKLFLYGKTGWIGGLLGKLCEKQGIPYEYGKGRLEDRSPILADIQAVKPTHVFNAAGVTGRPNVDWCESHKTETIRTNVIGTLTLADVCREHGLLRMNFATGCIFEYEDKPNFTGSFYSKTKAMVEELLKEYDNVCTLRVRMPISSDLNNPRNFITKIANYFKVINIPNSMTILDELLPITIEMAKRNLRGIWNFTNPGVVSHNEILEMYKTYIDPEFKWTNFTLEEQAKVIVAPRSNNEMDASKLKKEFPELLPIKESLIKVVFEPNKKT

Ligand/Cofactor

UDP-glucose

C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O

Validation Metrics

PLDDT	86.6
NLMSIM	60.0
AACOMP	93.5
Seqdif (SeqID)	14.8 (PPR93353.1)
Structdif (F-Target)	4.0 (2hun B)

ProtNLM

Name	Score
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1	0.225
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1-like	0.217
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2	0.058
Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2-like	0.050
Rhamnose biosynthetic enzyme 1	0.042
UDP-glucose 4,6-dehydratase	0.034