MV2M0

Prompt

1.4.1.9

Oxidoreductases. Acting on the CH-NH2 group of donors. With NAD(+) or NADP(+) as acceptor. leucine dehydrogenase.

AI Generated Sequence

366 AAs

MSVFEYIEFDDHEQVVFCHDKASGLKAIIAIHDTTLGPALGGTRMWPYASEEEAIYDALRLARGMTYKNAAAGLNLGGGKAVIIGDPKKDKNEAMFRAFGRYIQGLNGRYITAEDVGTTVEDMDIIHEETDYVTGVSKAFGSSGNPSPVTAYGVYRGMKAAAKEAFGTDSLEGKTIAVQGVGNVAYNLCRHLHEEGAKLIVTDINKENVQRAVKEFGATAVEPDEIYGQDCDIYAPCALGATINDQTIPQIKCKVIAGAANNQLKETRHGDIIHEMGILYAPDYVINAGGVINVADELYGYNRERAMKKVETIYNTIAEVLEISKRDGIPTYQAADRMAEERIESMKKSRSQFLQNGHSILSRRGR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	92.5
NLMSIM	95.0
AACOMP	91.9
Seqdif (SeqID)	11.8 (WP_214704425.1)
Structdif (F-Target)	6.7 (8gxd A)

ProtNLM

Name	Score
Leucine dehydrogenase	0.727
Glu/Leu/Phe/Val dehydrogenase	0.127
1.4.1.9	0.074
Glutamate dehydrogenase/leucine dehydrogenase	0.012
NADP-specific glutamate dehydrogenase	0.010
Amino acid dehydrogenase	0.005