MV01E

Prompt

6.2.1.13

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. acetate--CoA ligase (ADP-forming).

AI Generated Sequence

500 AAs

MSEKIYPVPKEWAKNAHIDNEKYLKMYEESINDPEKFWGKHGKRIDWFKPYTKVKNTSFDKDVSIKWFEDGKTNVSYNCIDRHLKTRGDQTAIIWEGDNPYVEKKITYNELHEHVCRMANVLKKHGVKKGDRVTIYMPMIPEAAYAMLACARIGAIHSVVFGGFSPDALAGRIEDCESTFVITADEGVRGGKPVPLKENTDKAIDIAKKHNVEKVIVVHRTGGKVGMVEGRDYWYHEEVEKVSDHCEPEKMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYVFDYHDGDVYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPTYPDSSRFWQVCDKHKVNIFYTAPTAIRALMREGDEHVKKTSRKSLRLLGSVGEPINPEAWEWYYNVVGDKRCPIVDTWWQTETGGILITPLPGATDLKPGSATRPFFGVKPALVDEEGKELEGATEGNLCIKDSWPGQMRTVYGDHQRFIQTYFSTYKGKYFTGDGC

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	90.6
NLMSIM	70.0
AACOMP	90.6
Seqdif (SeqID)	14.7 (TCS27048.1)
Structdif (F-Target)	3.0 (7kdn C)

ProtNLM

Name	Score
Acs	0.291
6.2.1.1	0.166
Acetyl-coenzyme A synthetase	0.161
Acetate--CoA ligase	0.147
AcCoA synthetase	0.115
Acyl-activating enzyme	0.113