MUZPF

Prompt

1.3.1.25

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase.

AI Generated Sequence

411 AAs

MKKVAIITGGAQGIGLAIAKELAKKGADVILADIDEEKLKEVAEELRKEFPELKGKGKGKILKADVTKEEDVKAAVEAIKEKFGKIDILINNAGIGKGGTFLDMDLEAIKRTIDINLWGTFLTTKAVIPKMKEGKGRIINIGSVAGLEGAPFQNVYAASKAAVIGLTKTLALELAKEKGIHVNGIYPGFKTDILGAILGDELKDFIKKHPEHGHGPEEIYNAAVYFLGSEKAAEYINGGAVHVGGGTLWLKGKEEKKLLKEKLAGKVALKGAKGCGYPANPRLMTPEMFAKHFAGGGAKVIALDRNEEKLKEVKEEIRPLLGKEVELLTCDVTKEEDVKAAVEAIKEKFGKIDILVNAGIAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	75.0
NLMSIM	70.0
AACOMP	80.3
Seqdif (SeqID)	52.2 (WP_090552223.1)
Structdif (F-Target)	8.5 (6ihi A)

ProtNLM

Name	Score
SDR family oxidoreductase	0.374
SDR family NAD(P)-dependent oxidoreductase	0.151
Short-chain dehydrogenase	0.084
1.1.1.100	0.048
Short-chain dehydrogenase/reductase SDR	0.039
Glucose 1-dehydrogenase	0.037