MUVL4

Prompt

1.1.1.60

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 2-hydroxy-3-oxopropionate reductase.

AI Generated Sequence

344 AAs

MKIGFIGLGIMGTPMARNLLKAGHELFVHSRGPAPDELVAAGATACASAKEVAERAEVIITMLPDTPDVEAVLFGENGVAAGLSKGKLVVDMSSISPLETKRFAKRINELGCDYLDAPVSGGEVGAKAGSLTIMVGGPEAAFERAKPLFELMGKNITLVGDNGDGQTCKVANQIIVALTIEAVGEALLFASKAGADPAKVRQALMGGFASSRILEVHGERMIKRTFNPGFRIELHQKDLNLALQGARALGLALPNTANAQQLFNTCAANGGKEWDHSAMVRALELMANHEIGREKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	97.3
NLMSIM	90.0
AACOMP	84.4
Seqdif (SeqID)	18.9 (HXF66514.1)
Structdif (F-Target)	3.1 (1vpd A)

ProtNLM

Name	Score
2-hydroxy-3-oxopropionate reductase	0.525
1.1.1.60	0.321
Tartronate semialdehyde reductase	0.126
Tartronate semialdehyde reductase, NADH-dependent	0.017
TSAR	0.002
NAD(P)-dependent oxidoreductase	0.001