MURFI

Prompt

1.2.1.n2

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. fatty acyl-CoA reductase.

AI Generated Sequence

509 AAs

MSLPEFYEGKSFLLTGGTGFLGKVLLEKLLRSCPEVKNVYLLIRPPKGQAPEERVRELMNSKLFDKVREVHNEFLEKITAISGDVTEPNLGISDEDKEAILESVNIVFHAAATVRFDERLRDAVQLNVTGTRQLLNFCKQMKNLEAFLHVSTAYVNCNRNGIEEVIYPPPVDPKKLIDAMEWLDGSLMDITKPLLGDRWPNTYFTKALAGEYVVQEGGDLNVAIIRPSIVGSAWKEPFPGWIDNFNGPSGLIAAAGKGILRTLMGTDNAVADLIPVDVVVNTLLAAAWYAAVNRPKNLVYNCTTSTQNPFNWQEVEGHVASSFRRFPLEQAFWRPNANITSNNLFYQWQMIVSHKVPALLYDILYRLTGKPRMMKTIMRHLKAVMDLLEYFTRSWEFDTDNMERLMQSLTPDERKFFNFDVRTIDWDEYIENYILGTKKYLLKEEMTDVPEKARNYHLKNLRRYSYAFTFTILVIWRILIASQARSLGRNVWFCVDSVYKFLRYFRISS

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.5
NLMSIM	95.0
AACOMP	94.5
Seqdif (SeqID)	37.0 (XP_042547259.1)
Structdif (F-Target)	14.6 (7eoz B)

ProtNLM

Name	Score
Fatty acyl-CoA reductase	0.520
1.2.1.84	0.462
Fatty acyl-CoA reductase 1	0.007
Fatty acyl-CoA reductase 2	0.002
Fatty acyl-CoA reductase 1-like	0.001
FACR1 reductase	0.001