MUMII

Prompt

1.1.1.343

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating).

AI Generated Sequence

534 AAs

MAKLGLIGLGVMGGNMALNLAKKGFEVVGYNRTTAKVDELVKGAKAKGKLKGYETLEEFVAKLKKPRKIMMLVKAGAPVDATIEALVPLLEEGDIIIDGGNSHYTDTIRRTKELEAKGILYVGCGVSGGEEGARHGPSLMPGGSPEAYAHIKPIFQAIAAKADDGEPCTEWIGDGGAGHYVKMVHNGIEYGDMQLICEAYHLMKKGLGLSNDEMHDVFAEWNKGELDSYLIEITADIFKYKDDDGKYLLDKILDTAGQKGTGKWTIASALDYGVPVTLITESVFARCLSALKDERVAAAKVLGGPAPKFTGDKAAFVEDLRQALYASKICSYAQGFMLMREAAKEYGWDLNYGNIALMWRGGCIIRSVFLGKIKDAYDRNPDLENLLFDDFFKKAIENAQAGWREVVAKAILYGIPAPAFSAALAYYDGYRSARLPANLLQAQRDYFGAHTYRRVDLPRGEFFHTEWTGRGGNVSASTYQAAGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	87.0
NLMSIM	70.0
AACOMP	86.0
Seqdif (SeqID)	26.5 (HHV96755.1)
Structdif (F-Target)	2.0 (3fwn B)

ProtNLM

Name	Score
1.1.1.44	0.619
6-phosphogluconate dehydrogenase, decarboxylating	0.368
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	0.004
NADP-dependent phosphogluconate dehydrogenase	0.002
Decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase	0.001
6PGD domain-containing protein	0.001