MULZY

Prompt

1.13.11.57

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. gallate dioxygenase.

AI Generated Sequence

278 AAs
MAGEIIGGLATSHSPTIGFALDKAKDVAKWQPIFEGYQPIHEWLAEKKPDVLFIIYNDHVTSFFFDHYSAFTLGVADTYQADGDGGGRRPLPPVKGHPELARHIASSLMADEFDMTMFQEMPLDHGCFVPLSMLCPENGWPVKVIPLQVGVLQYPPASARRCFKLGQALRRAIESYPEDLNVAVIATGGLSHQVHGERTGFNNPEWDARFLDLMEQDPAKFAAMTLQEYAELGKGEGAEIIMWLVMRGALSAKVTRLHRSYYLPMSTGIATIWLENHE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT83.5
NLMSIM80.0
AACOMP95.0
Seqdif (SeqID)29.1 (WP_099740153.1)
Structdif (F-Target)5.3 (1bou D)

ProtNLM

NameScore
Protocatechuate 3,4-dioxygenase0.218
Gallate dioxygenase0.203
Protocatechuate 4,5-dioxygenase beta chain0.144
1.13.11.80.099
LigB domain-containing protein0.076
Protocatechuate 4,5-dioxygenase beta subunit0.060
Designed by MP, using an AMD MI250 GPU