MUE7W

Prompt

1.5.7.1

Oxidoreductases. Acting on the CH-NH group of donors. With an iron-sulfur protein as acceptor. methylenetetrahydrofolate reductase (ferredoxin).

AI Generated Sequence

286 AAs
MKIKDFIKNKKFVFSAEFFPPKTEESIENIYKTIDELKELNPDFISVTYGAGGSTRERTLEIASKIQKDYGIETVAHLTCVDLTKEEITDILNKYKEEGIKNILALRGDLPKGEKFEATKDFKYADSQLIKFIKENGFDFCIGAACYPEGHPESPNFESDIEHLKKKVDAGTDFLITQMFFDNDKFYDFLDKIKAIGITVPIIPGIMPITNAKQLKRMTSLCGASIPSKFINILEKYKDNPEALKEAGIKYATEQIIDLIDNGVNGIHLYTMNKPEATKKIWESLK

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT90.1
NLMSIM60.0
AACOMP86.3
Seqdif (SeqID)40.7 (WP_106024320.1)
Structdif (F-Target)4.7 (7th5 B)

ProtNLM

NameScore
1.5.1.200.548
Methylenetetrahydrofolate reductase0.440
Methylenetetrahydrofolate reductase [NAD(P)H]0.004
Methylenetetrahydrofolate reductase (NAD(P)H)0.004
Methenyltetrahydrofolate cyclohydrolase0.001
5,10-methylenetetrahydrofolate reductase0.001
Designed by MP, using an AMD MI250 GPU
EC Repo - MUE7W | 310.ai