MUDO1

Prompt

1.3.1.98

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. UDP-N-acetylmuramate dehydrogenase.

AI Generated Sequence

343 AAs

MKLLDDLSSLPRLTRFGLRPGAERFARVTFRDGGIAALVAPEIDDTDLLVLGGGSNLLLPDDIFGVGVSNMIVRDGVVGDGVVLLGERFAAGEPWDDFVRTAGAGQPLGAVENLSIPGTVGASPFMQNIGTGVELSDTFDSGCAYDRETGELVRLTNRDCGFRYRESLKAEGFDYRIITHVEARWLVPKARFEAKYGPVERAIEAEVDGVPTLREVSQPVIDKRKASLFKNPDPHNSGSFFKNPIVGRQRIGALQKELPHMNFYNPDGTATKLDAGWLIERAGFKGFREGGVGVWSKHALLVNVGGNATGEQLMDLARTIRDSVAKEVGVELEMEPVFIGVGA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	74.3
NLMSIM	70.0
AACOMP	92.5
Seqdif (SeqID)	58.2 (WP_084919466.1)
Structdif (F-Target)	7.2 (7orz A)

ProtNLM

Name	Score
UDP-N-acetylenolpyruvoylglucosamine reductase	0.363
1.3.1.98	0.333
UDP-N-acetylmuramate dehydrogenase	0.299
6.3.2.-	0.000
UDP-N-acetylmuramoyl-L-alanine synthetase	0.000
6.3.2.8	0.000