MU83C

Prompt

6.2.1.45

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. E1 ubiquitin-activating enzyme.

AI Generated Sequence

499 AAs

MQDNMVKNGSEIDESLYSRQLYVLGHEAMKRMGASNVLIVGLKGLGVEIAKNIALAGVKSVTLYDPKPVSISDLSSQFFLQPEDVGKPRDEVTAPRVAELNSYVPVKVHESGELTDTLSQLKKYQVVVLTNTPLKDQLKIGDFCHSNGIYVIATDTFGLFGSIFTDFGKNFTVCDPTGEEPLSGIVAGIDKDGLVTVLDETRHGFEDGDYVTFTEVKGMEGLNGCEPRKIEVLGPYTFSIGDVSGLGTYQRGGLYTQVKMPKFINFKSLSEQLKKPEFVISDFAKFDRPAQLHIGFQALHKFQEVHGRLPRPWHNEDAEEVLKIAKNIAKETGLKVEELDEKLIKELSYQARGDLNPMAAFFGGLAAQEVLKSVSGKFHPVKQWLYFDSLESLPSSTKRSEELCKPLGSRYDGQIAVFGKEYQEKINNLTQFLVGAGAIGCEMLKNWAMIGLATGPKGKITVTDMDQIEKSNLNRQFLFRPKDVGKLKSECAAKAVQLM

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	94.6
NLMSIM	90.0
AACOMP	93.3
Seqdif (SeqID)	23.9 (RKU45084.1)
Structdif (F-Target)	6.0 (6nya A)

ProtNLM

Name	Score
UBA_e1_C domain-containing protein	0.253
Ubiquitin-activating enzyme E1	0.223
Ubiquitin-activating emzyme E1	0.206
Ubiquitin-activating enzyme E1 1	0.068
Ubiquitin-like modifier-activating enzyme 1	0.029
6.2.1.45	0.015