MU57I

Prompt

1.5.1.36

Oxidoreductases. Acting on the CH-NH group of donors. With NAD(+) or NADP(+) as acceptor. flavin reductase (NADH).

AI Generated Sequence

473 AAs

MSDRPVVVVGGGWGAGLALARRLGRDAVEVTVVDRNNFHTFQPPLLPVAVGRLSGRSVWPELEAHFARRHNVRLLQEEVTDIDAATRTVRLADGGEVAYDALVIALGGESNFFGIPGLERHAHPGLSIEDALAIRRHVLANFARAEPLTDEARRRRLLTFVIVGGGPTGVELAGELHDMVDRTLPDYFRRIDRREARIHLIEAGDRILPAFADRLSAYAERQLRELGVDVLTGTRVADCAAHGVTTRDGREIEAEMVVWAAGVASPAIGRALGAEQTRRRQLVVDPHLRTVPGDEVFAVGDCASVTPDGTRGHLPGVAQAAQQAGEYVARNIAARLAGRPLAPFAYRDHGSLATIGRNAAVADLGFGLRLSGFAAEWLWWAVHLALFVSTRNRLRVVTNWALNYLTWDRSLRIITGRQHRAERAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT	90.6
NLMSIM	65.0
AACOMP	83.7
Seqdif (SeqID)	47.6 (HMM34231.1)
Structdif (F-Target)	6.8 (5na1 A)

ProtNLM

Name	Score
NADH dehydrogenase	0.300
NAD(P)/FAD-dependent oxidoreductase	0.180
FAD-dependent oxidoreductase	0.134
1.6.99.3	0.102
NADH dehydrogenase FAD-containing subunit	0.051
FAD-dependent pyridine nucleotide-disulfide oxidoreductase	0.042