MU1JG

Prompt

1.2.1.36

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. retinal dehydrogenase.

AI Generated Sequence

498 AAs

MAPTHYRVKLNDGKNMIPGFGTWASKPKPAGEVYKSAVKAIDVGYRHFDCADVYNNEKEIGQAFQAKWKEGVAKREDIFIVSKLWSCTHERPLLRPTLEKTLNKLQLDYVDLYLIHFPFTFKPGKELYPVDENGKVIPDSTFDYATWEAMEECVVLGWVKNIGVSNFNHKQIARILLNPGCTLKPAVLQVECHPYLLQNKLLEGFQPKGINVVTYGPLGSQTRPWSVHPDSKVLFDSPTVAAIAKKHKKTAAQVLIRFQLNGKSVVIVSSEDPERIEQNLQVFDFLFTGSGMMCIASLNRNHYVSILDFTERHKPYVKFEELFGDPFNETTKMGPQISKEHMKELLSYIKIGKEEGAKLLCGGEAVHEGKGYFIKPTVFADTQDDMKITKETIFGPVLAILRFKTEEEALAISNSTNFGLAAGVFTQDLKRAHVIAQLELAGRVWINCYNLVVPARFPFGGKMSGVGRFLGKYGLDRYSPKTLSIDMPLKKNSWKEVK

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	82.5
NLMSIM	70.0
AACOMP	93.2
Seqdif (SeqID)	46.0 (XP_036617079.1)
Structdif (F-Target)	4.1 (4wdw A)

ProtNLM

Name	Score
Aldehyde dehydrogenase family 1 member B1	0.132
Aldehyde dehydrogenase family 1 member B3	0.128
Aldehyde dehydrogenase family 1 member B4	0.110
Aldehyde dehydrogenase family 1 member B7	0.082
Aldehyde dehydrogenase, mitochondrial	0.047
Aldehyde dehydrogenase 1 family member B1	0.047