MTXVI

Prompt

1.1.1.271

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. GDP-L-fucose synthase.

AI Generated Sequence

315 AAs

MTDKRIFVAGHRGMVGSAIVRRLEARGYDELIARTHDELDLTRNQAVADFFAAERPDQVFYLAAAKVGGIVANSTYPADFIYENMLIEQNVIHAAYLNGVKKLLFLGSSCIYPKLAPQPMKESELLTGELEPTNEPYAIAKIAGIKLCESYRRQYGRDFRSVMPTNLYGPHDNFDLNNSHVLPALIRRFHEAKANGAPEVVVWGSGTPLREFLHVDDMADACVFVMENYTGPELHVNVGTGVDCTIRELAQTVAKVVGYTGEIVFDTSKPDGTPRKLMDVSRLQALGWTPKISFEEGLAATYRWFLENQDRLRAG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	93.0
NLMSIM	70.0
AACOMP	96.1
Seqdif (SeqID)	24.6 (EMB1382381.1)
Structdif (F-Target)	4.0 (1bsv A)

ProtNLM

Name	Score
GDP-L-fucose synthase	0.448
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.361
1.1.1.271	0.183
NAD-dependent epimerase/dehydratase family protein	0.001
GDP-L-fucose synthetase	0.001
GDP-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.000