MTT5X

Prompt

1.1.1.17

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. mannitol-1-phosphate 5-dehydrogenase.

AI Generated Sequence

444 AAs

MKKAVHFGAGNIGRGFIGYLLAEAGYEVTFADVNEPLIDALNKRGSYTVHEVAEGKCEITVNNVRAVNSKAPEAVLDAIAKADLVTTAVGPNILDIIAPTIAKGIEARKAAGNTQPLNVIACENMIGGTSHLKSEVYAHLDDALKAEAEKYVGFPDSAVDRIVPPQSAHNDPLQVTVEKFSEWIVDKTQFKGPIPQINGMEYVDNLMPYVERKLFTLNTGHCITAYLGCLKGHKTIRDAIEDEAIHAAVRGVMQETGAVLIKRYAFDAAKHAAYIEKILGRFANPYLVDEVDRVGRQPLRKLGFNDRLIKPLGETLERGLPNKNLLKTIAAALKFRNDEDPQSVELQAMIAEKGVAGTLAEYTGLAADSPLVAEIVALYNKMKAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAAKKAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	95.8
NLMSIM	90.0
AACOMP	86.7
Seqdif (SeqID)	30.5 (WP_085319867.1)
Structdif (F-Target)	1.4 (3h2z 2)

ProtNLM

Name	Score
Mannitol-1-phosphate 5-dehydrogenase	0.690
1.1.1.17	0.303
MPD	0.001
M1PDH	0.001
Polyol:NADP oxidoreductase	0.000
Fructuronate reductase	0.000