MTQI2

Prompt

1.14.11.7

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. procollagen-proline 3-dioxygenase.

AI Generated Sequence

500 AAs

MQNIEQYRAMAGVKEATLIDREAKPHMESYDAGVRHYEKEDFELAIGFFERALQEYFSADADCRALCEGPQRFEEGEYLNYGADLYEAIADHYMQVLACQHDCVRELATRSGRLSPIEDFLPLHYDYLQFAYYRVGDYTKALECAKSYLLFHPDDEDVLDNLDYYEGLLEGAMDPAIIRPREDLKTYMRRHLLESELLYYAAADLGISYTEPDYWNRVGGRQADREQGREPEPVRVPSSIGMEPEEIEHLSLAKKKSLPKDRELREGGPLLYSDVKFVMNSQQLNGTQRVLLDNVISEEQCRELHRLANAIMLAGDGYRGKTSPHTPNEKFEGATVLKALKLGYEGRVPLRSARLFYDVSEKARRIVESYFLLNTPLYFSYTHLVCRTAISGQQERNDLSHPIHADNCVLDPEANECWKEPPAYTFRDYSALLYMNADFEGGEFIFTEMDAKTVTASIKPKCGRMISFSSGGENPHGVKAVTKGQRCAVALWFTLDPRHR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	73.6
NLMSIM	90.0
AACOMP	93.3
Seqdif (SeqID)	19.2 (XP_009929969.1)
Structdif (F-Target)	18.0 (4j25 G)

ProtNLM

Name	Score
Procollagen-proline 3-dioxygenase	0.725
1.14.11.7	0.258
Prolyl 3-hydroxylase 2	0.011
P3H2 hydroxylase	0.001
PKHD1L1	0.000
Fe2OG dioxygenase domain-containing protein	0.000