MSN4O

Prompt

1.1.1.308

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. sulfopropanediol 3-dehydrogenase.

AI Generated Sequence

500 AAs

MAREYLKKALKTETGDAAEVTEKVAGILDDIETRGDKAALDYAEKFDKWEGDIRLSPEEIRAAIDGVPEKVLKDIEFAHRQVRKFAERQRESLTDVEIETLPGIRAGHKAIPVNAVGCYVPGGRYAHIASAVMAVATAKVAGVKHIVACSPPRPDGVAPAMVYAAQMCGADEILAMGGVQAIAAMAYGLFTGKPADILVGPGNQFVAEAKRQLFGRVGIDMIAGPTELSILADETADPEIVATDLVGQAEHGYNSPAWLVTTSRKLAEEVMARVPELIETLPVVARNECARESWRDYGEVIVCDDREEMVAFSDRYASEHLQVMTEDMDWFLDRLTCYGSLFLGEETNVAYGDKASGTNHVLPTKGAARYTGGLSVHKFMKIVTWQRLTREGSQEIGVVTSRISLLEGMEGHARTADVRLAKYFPETDFPYETEGEFETETETETETETETETETETETETETETETETETETETETETETETETETETETETETETETE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.2
NLMSIM	60.0
AACOMP	87.9
Seqdif (SeqID)	28.9 (WP_037270270.1)
Structdif (F-Target)	7.7 (4g09 2)

ProtNLM

Name	Score
Histidinol dehydrogenase	0.301
1.1.1.23	0.265
Sulfopropanediol 3-dehydrogenase	0.158
1.1.1.308	0.134
DHPS 3-dehydrogenase (sulfolactate forming)	0.051
2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming)	0.033