MSCUT

Prompt

3.1.6.4

Hydrolases. Acting on ester bonds. Sulfuric ester hydrolases. N-acetylgalactosamine-6-sulfatase.

AI Generated Sequence

502 AAs

MKRLLLLLLLLLLLLLPLLLPLPLPPPPPNILFLLADDHGYRDLGAYGNPLVRTPNLDRLAAEGVRFENAYAANPLCSPSRASILTGLYPSHVGVLTNINGRVPGSLLPLLREAGYNTALIGKWHLGGEPGFGQHWSHPLQRGFDWYYGVPGGSNYYNPSLVYRNDVLKEVPRKEGYYSDLITDKAIDFIERRRDEKPFFLALHFAKPHHPWQAPEKYIDLYDKELPLPELPEEEFRRRMLRYYGAMVSHVDLNVGRILDALEKLGLLDNTLVVFTSDNGEFLGEHGLFWKKYSYYEGGIRVPLIVRWPGLIPAGTVSSELVSNIDFAPTLLDLAGVPVPPDMQGRSLLPLLRGESLPWREHLFYEYYHHVAVRGDWKLIHYTNWTELYDLNRDPGELNNLADEPYREVLERLRELLEEYRERNLPELEELYRGLLGEGEPLPPLPLPLPPLPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP

Ligand/Cofactor

N-acetyl-D-galactosamine 6-sulfate

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)O)O

Validation Metrics

PLDDT	87.1
NLMSIM	60.0
AACOMP	82.1
Seqdif (SeqID)	59.5 (WP_146659888.1)
Structdif (F-Target)	8.6 (6hr5 A)

ProtNLM

Name	Score
Sulfatase	0.384
Sulfatase-like hydrolase/transferase	0.153
Arylsulfatase A	0.080
DUF4976 domain-containing protein	0.059
Sulfatase domain-containing protein	0.048
3.1.6.1	0.045