MSBFN

Prompt

2.1.1.173

Transferases. Transferring one-carbon groups. Methyltransferases. 23S rRNA (guanine(2445)-N(2))-methyltransferase.

AI Generated Sequence

711 AAs

MSDRFELFATCPRGLEGLLAEELAGLGAEAAREVAAGVRAEGDLALAYRLCLWSRLANRVLLPLAGFRARDAADLYAGVAAVDWPEHFGPDRTLAVDFSGTRGEIRNTHFGALKVKDAIVDRLRERLGRRPSVDKERPDLRVHVLLRRDEAVLSLDLSGDSLHQRGYRLAQGAAPLKENLAAAILVRAGWPGGGGGGGTLLDPMCGSGTFLIEAALMGADIAPGLRRERWGFSAWLGHDPALWRRLREEAEARARAGLARLPRWLYGYDADPRVIRPARANAERAGVADWIRFEQGDVAAFEPPPPGPRLGVVVCNPPYGERLGEEPALLALYAVLGERLRRACGGWNAAVFTGSPELLGRLGIRADKQFKFWNGALPCKLQNYRVTERETRDAEAAREAGEMFANRLRKNLKLLGKWAKREGVNCYRLYDADMPEYALAVDRYGDHVHVQEYAAPKSIDPEKARQRLLDVIATLPRVTGVDPRRVVLKTRERQKGTKQYEKQAKEGEFVRVTEHGARLLVNLTDYLDTGLFLDHRLTRRRLQGEARGKRFLNLFCYTGTATVHAALGGARSTTSVDLSRTYLDWARRNFALNGLTGRRHRLVQADCLGWLREARERFDLIFVDPPTFSNSKRMEDVFDVQRDHVALMQRAVARLAPGGVLYFSNNFRKFRMDEGLAELGYRAVEDITERTLEPDFARNPRIHNAWLITHA

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	91.9
NLMSIM	90.0
AACOMP	89.7
Seqdif (SeqID)	31.9 (WP_158895915.1)
Structdif (F-Target)	7.4 (3v97 A)

ProtNLM

Name	Score
23S rRNA m2G2445 methyltransferase	0.244
2.1.1.264	0.200
Ribosomal RNA large subunit methyltransferase K/L	0.156
23S rRNA m7G2069 methyltransferase	0.127
RRNA (guanine-N(7)-)-methyltransferase RlmK	0.127
RRNA (guanine-N(2)-)-methyltransferase RlmL	0.093