MSB84

Prompt

3.1.6.4

Hydrolases. Acting on ester bonds. Sulfuric ester hydrolases. N-acetylgalactosamine-6-sulfatase.

AI Generated Sequence

294 AAs

MKKPNILFIMTDHLRWDSIGCYGNEFSKTPNIDRLAKEGVLFEQAFVSNPLCPASRASILTGKYPSHHGVTDNNGRAPDQVSIPKLEETTLPEKLKEAGYKTAIVGKWHLGKEVPQGFDFWSVVPGGGKYYDPAFVKRGNVVAEEKVPLEGYVTDLITEKALDFIDARKDEPFFLMYSFTAPHTPWCPPKHFVDLYKDPDIPEPKKLDEPKYKKWMEEYLDGVRSVDDNVGRLLDYLDKNGLADNTIVIFTSDHGPFLLEHGLAGYGLLLTPDGKWLTDWLKKHKLLKKLKKLK

Ligand/Cofactor

N-acetyl-D-galactosamine 6-sulfate

CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)O)O

Validation Metrics

PLDDT	81.3
NLMSIM	60.0
AACOMP	89.7
Seqdif (SeqID)	58.4 (WP_146659888.1)
Structdif (F-Target)	10.1 (2qzu A)

ProtNLM

Name	Score
Sulfatase	0.457
Sulfatase domain-containing protein	0.404
Sulfatase-like hydrolase/transferase	0.049
Arylsulfatase	0.030
DUF229 domain-containing protein	0.016
Arylsulfatase A	0.007